Biotinylated Recombinant Human HLA-G Complex Protein

Produktübersicht

• Artikelname: Biotinylated Recombinant Human HLA-G Complex Protein
• Artikelnummer: ABB-RP02751
• Hersteller Artikelnummer: RP02751
• Alternativnummer: ABB-RP02751-100UG
• Hersteller: ABclonal
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Immunogen: Gly25-Thr305(HLA-G),Ile21-Met119(B2M) and RIIPRHLQL peptide
• Alternative Synonym: HLA G antigen, sHLA-G, b2 microglobulin, HLA G, HLAG, HLA-G, MHC Class I Antigen G, MHC class Ib antigen, MHC-G, sHLA-G

Produktbeschreibung

HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition.

Produkteigenschaften

• Konzentration: < 1 EU/µg of the protein by LAL method.
• Molekulargewicht: 50.5 kDa
• NCBI: 3135
• UniProt: P17693
• Reinheit: 95 % as determined by Tris-Bis PAGE, 95 % as determined by HPLC.
• Target-Kategorie: HLA-G Complex

Anwendungsbeschreibung

• Anwendungsbeschreibung: Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles. ResearchArea: Other Recombinant Protein