Biotinylated Recombinant Human HLA-G Complex Protein
Biozol Catalog Number:
ABB-RP02751
Supplier Catalog Number:
RP02751
Alternative Catalog Number:
ABB-RP02751-100UG
Manufacturer:
ABclonal
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Immunogen:
Gly25-Thr305(HLA-G),Ile21-Met119(B2M) and RIIPRHLQL peptide
Alternative Names:
HLA G antigen, sHLA-G, b2 microglobulin, HLA G, HLAG, HLA-G, MHC Class I Antigen G, MHC class Ib antigen, MHC-G, sHLA-G
HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition.
95 % as determined by Tris-Bis PAGE, 95 % as determined by HPLC.
Target:
HLA-G Complex
Application Notes:
Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles. ResearchArea: Other Recombinant Protein
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