Recombinant Mouse Hepcidin/HAMP Protein, E. coli

Produktübersicht

• Artikelname: Recombinant Mouse Hepcidin/HAMP Protein, E. coli
• Artikelnummer: ABB-RP02870LQ
• Hersteller Artikelnummer: RP02870LQ
• Alternativnummer: ABB-RP02870LQ-100UG
• Hersteller: ABclonal
• Wirt: E. coli
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Mouse
• Immunogen: Asp59-Thr83
• Alternative Synonym: Hamp1, Hepc, Hepc1, HFE2B, LEAP1, LEAP-1, PLTR

Produktbeschreibung

Hepcidin, the main regulator of iron metabolism, is synthesized and released by hepatocytes in response to increased body iron concentration and inflammation. Deregulation of hepcidin expression is a common feature of genetic and acquired iron disorders: in Hereditary Hemochromatosis (HH) and iron-loading anemias low hepcidin causes iron overload, while in Iron Refractory Iron Deficiency Anemia (IRIDA) and anemia of inflammation (AI), high hepcidin levels induce iron-restricted erythropoiesis.

Produkteigenschaften

• Konzentration: < 1 EU/µg of the protein by LAL method.
• Molekulargewicht: 29.05 kDa
• Tag: N-GST
• NCBI: 84506
• UniProt: Q9EQ21
• Quelle: E. coli
• Reinheit: 95 % as determined by SDS-PAGE.
• Formulierung: Supplied as a 0.22 µm filtered solution in 50 mM Tris-HCl, 150 mM NaCl, 2 mM DTT, pH 7.5.
• Sequenz: DTNFPICIFCCKCCNNSQCGICCKT
• Target-Kategorie: Hepcidin/HAMP

Anwendungsbeschreibung

• Application Verdünnung: Supplied as a 0.22 µm filtered solution in 50 mM Tris-HCl, 150 mM NaCl, 2 mM DTT, pH 7.5.
• Anwendungsbeschreibung: ResearchArea: Other Recombinant Protein