Recombinant Mouse Hepcidin/HAMP Protein, E. coli

Product Overview

• Article Name: Recombinant Mouse Hepcidin/HAMP Protein, E. coli
• Biozol Catalog Number: ABB-RP02870LQ
• Supplier Catalog Number: RP02870LQ
• Alternative Catalog Number: ABB-RP02870LQ-100UG
• Manufacturer: ABclonal
• Host: E. coli
• Category: Proteine/Peptide
• Species Reactivity: Mouse
• Immunogen: Asp59-Thr83
• Alternative Names: Hamp1, Hepc, Hepc1, HFE2B, LEAP1, LEAP-1, PLTR

Product Description

Hepcidin, the main regulator of iron metabolism, is synthesized and released by hepatocytes in response to increased body iron concentration and inflammation. Deregulation of hepcidin expression is a common feature of genetic and acquired iron disorders: in Hereditary Hemochromatosis (HH) and iron-loading anemias low hepcidin causes iron overload, while in Iron Refractory Iron Deficiency Anemia (IRIDA) and anemia of inflammation (AI), high hepcidin levels induce iron-restricted erythropoiesis.

Product Properties

• Concentration: < 1 EU/µg of the protein by LAL method.
• Molecular Weight: 29.05 kDa
• Tag: N-GST
• NCBI: 84506
• UniProt: Q9EQ21
• Source: E. coli
• Purity: 95 % as determined by SDS-PAGE.
• Form: Supplied as a 0.22 µm filtered solution in 50 mM Tris-HCl, 150 mM NaCl, 2 mM DTT, pH 7.5.
• Sequence: DTNFPICIFCCKCCNNSQCGICCKT
• Target: Hepcidin/HAMP

Application Notes

• Application Dilute: Supplied as a 0.22 µm filtered solution in 50 mM Tris-HCl, 150 mM NaCl, 2 mM DTT, pH 7.5.
• Application Notes: ResearchArea: Other Recombinant Protein