Human CD22 Monoclonal Antibody, Endotoxin 0.05 EU/mg
Artikelnummer:
ABB-YR0114
Hersteller Artikelnummer:
YR0114
Alternativnummer:
ABB-YR0114-5MG,ABB-YR0114-20MG
Hersteller:
ABclonal
Kategorie:
Antikörper
Applikation:
ELISA, NeA
Immunogen:
Human CD22
Alternative Synonym:
SIGLEC2, SIGLEC-2
Epratuzumab is a humanized monoclonal antibody derived from the murine IG2a monoclonal antibody, LL2 (EPB-2). This agent may subsequently be well matched for use in oncology and the treatment of inflammatory autoimmune disorders, such as lupus.Epratuzumab is a recombinant, humanized monoclonal antibody directed against CD22, a cell surface glycoprotein present on mature B-cells and on many types of malignant B-cells. It binds with high specificity to normal B-cells and B-cell tumors at the third Ig-like domain of CD22. After binding to CD22, epratuzumabs predominant antitumor activity appears to be mediated through antibody-dependent cellular cytotoxicity (ADCC).
