Human CD22 Monoclonal Antibody, Endotoxin 0.05 EU/mg
Biozol Catalog Number:
ABB-YR0114
Supplier Catalog Number:
YR0114
Alternative Catalog Number:
ABB-YR0114-5MG,ABB-YR0114-20MG
Manufacturer:
ABclonal
Category:
Antikörper
Application:
ELISA, NeA
Immunogen:
Human CD22
Alternative Names:
SIGLEC2, SIGLEC-2
Epratuzumab is a humanized monoclonal antibody derived from the murine IG2a monoclonal antibody, LL2 (EPB-2). This agent may subsequently be well matched for use in oncology and the treatment of inflammatory autoimmune disorders, such as lupus.Epratuzumab is a recombinant, humanized monoclonal antibody directed against CD22, a cell surface glycoprotein present on mature B-cells and on many types of malignant B-cells. It binds with high specificity to normal B-cells and B-cell tumors at the third Ig-like domain of CD22. After binding to CD22, epratuzumabs predominant antitumor activity appears to be mediated through antibody-dependent cellular cytotoxicity (ADCC).
