In Vivo Grade Recombinant Anti-mouse PD-L1 Rat IgG2b Kappa Monoclonal Antibody (Clone 10F.9G2.1)
Artikelnummer:
ABB-YR0308
Hersteller Artikelnummer:
YR0308
Alternativnummer:
ABB-YR0308-5MG,ABB-YR0308-1MG,ABB-YR0308-25MG
Hersteller:
ABclonal
Kategorie:
Antikörper
Applikation:
FC, IHC
Immunogen:
mouse PD-L1 cDNA and mouse PD-L1 CHO transfectants
The rat anti-mouse PD-L1 monoclonal antibody 10F.9G2 (rat IgG2b kappa) reacts with the mouse PD-L1 protein (programmed death ligand-1, B7-H1 or CD274), a member of the B7 family of the Ig superfamily. PD-1 has two ligands, PD-L1 and PD-L2. It has been shown that in mouse models of melanoma, tumor growth can be transiently arrested via treatment with the anti-mouse PD-1 and anti-mouse PD-L1 antibodies which block the interaction between the PD-L1 protein and its receptor PD-1 protein. The 10F.9G2 monoclonal antibody blocks the binding of the mouse PD-L1 protein to the mouse PD-1 protein.
Reinheit:
>95% Determined by SDS-PAGE
Application Verdünnung:
In Vivo Grade Recombinant Mouse IgG2b Kappa Isotype Control Antibody
Anwendungsbeschreibung:
Cross-Reactivity: <1EU/mg (<0.001EU/µg)Determined by LAL gel clotting assay
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