In Vivo Grade Recombinant Anti-mouse PD-L1 Rat IgG2b Kappa Monoclonal Antibody (Clone 10F.9G2.1)

Catalog Number: ABB-YR0308
Article Name: In Vivo Grade Recombinant Anti-mouse PD-L1 Rat IgG2b Kappa Monoclonal Antibody (Clone 10F.9G2.1)
Biozol Catalog Number: ABB-YR0308
Supplier Catalog Number: YR0308
Alternative Catalog Number: ABB-YR0308-5MG,ABB-YR0308-1MG,ABB-YR0308-25MG
Manufacturer: ABclonal
Category: Antikörper
Application: FC, IHC
Immunogen: mouse PD-L1 cDNA and mouse PD-L1 CHO transfectants
The rat anti-mouse PD-L1 monoclonal antibody 10F.9G2 (rat IgG2b kappa) reacts with the mouse PD-L1 protein (programmed death ligand-1, B7-H1 or CD274), a member of the B7 family of the Ig superfamily. PD-1 has two ligands, PD-L1 and PD-L2. It has been shown that in mouse models of melanoma, tumor growth can be transiently arrested via treatment with the anti-mouse PD-1 and anti-mouse PD-L1 antibodies which block the interaction between the PD-L1 protein and its receptor PD-1 protein. The 10F.9G2 monoclonal antibody blocks the binding of the mouse PD-L1 protein to the mouse PD-1 protein.
Purity: >95% Determined by SDS-PAGE
Application Dilute: In Vivo Grade Recombinant Mouse IgG2b Kappa Isotype Control Antibody
Application Notes: Cross-Reactivity: <1EU/mg (<0.001EU/µg)Determined by LAL gel clotting assay