NALE Purified Human IgG4 Isotype Control Recombinant Antibody (Clone: QA16A15), Clone: [QA16A15], Monoclonal

Produktübersicht

• Artikelname: NALE Purified Human IgG4 Isotype Control Recombinant Antibody (Clone: QA16A15), Clone: [QA16A15], Monoclonal
• Artikelnummer: ABI-10-108
• Hersteller Artikelnummer: 10-108
• Alternativnummer: ABI-10-108-100UG
• Hersteller: Abeomics
• Wirt: Human
• Kategorie: Sonstiges
• Applikation: ELISA, FACS
• Alternative Synonym: IGHG4, immunoglobulin heavy chain constant region gamma 4,

Produktbeschreibung

IgG4 is the least abundant immunoglobulin present in the human serum. IgG4 is implicated in a unique process called fab-arm exchange (FAE) and limits the formation of immune complex. It has anti-inflammatory properties. IgG4 functions as a therapeutic antibody. It provides protection against allergy, prevents mast cell degranulation and has a harmful role in malignant melanoma. IgG4 may be associated with autoimmune diseases such as, autoimmune pancreatitis (AIP) type 1 and 2, Mikulicz syndrome, Kuttner€s tumor, Riedel€s thyroiditis and tubulointerstitial nephritis.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [QA16A15]
• Reinheit: Low Endotoxin, Azide-Free antibody was purified by affinity chromatography.
• Formulierung: Low Endotoxin

Anwendungsbeschreibung

• Application Verdünnung: QA16A15 is a recombinant human IgG4. It can be used as an isotype control when evaluating fully human, humanized, or chimeric antibodies. This product is suitable as an isotype-matched control for ELISA, immunoblotting, FACS, IHC, and functional studies.