NALE Purified Human IgG4 Isotype Control Recombinant Antibody (Clone: QA16A15), Clone: [QA16A15], Monoclonal
Biozol Catalog Number:
ABI-10-108
Supplier Catalog Number:
10-108
Alternative Catalog Number:
ABI-10-108-100UG
Manufacturer:
Abeomics
Host:
Human
Category:
Sonstiges
Application:
ELISA, FACS
Alternative Names:
IGHG4, immunoglobulin heavy chain constant region gamma 4,
IgG4 is the least abundant immunoglobulin present in the human serum. IgG4 is implicated in a unique process called fab-arm exchange (FAE) and limits the formation of immune complex. It has anti-inflammatory properties. IgG4 functions as a therapeutic antibody. It provides protection against allergy, prevents mast cell degranulation and has a harmful role in malignant melanoma. IgG4 may be associated with autoimmune diseases such as, autoimmune pancreatitis (AIP) type 1 and 2, Mikulicz syndrome, Kuttner€s tumor, Riedel€s thyroiditis and tubulointerstitial nephritis.
Clonality:
Monoclonal
Clone Designation:
[QA16A15]
Purity:
Low Endotoxin, Azide-Free antibody was purified by affinity chromatography.
Form:
Low Endotoxin
Application Dilute:
QA16A15 is a recombinant human IgG4. It can be used as an isotype control when evaluating fully human, humanized, or chimeric antibodies. This product is suitable as an isotype-matched control for ELISA, immunoblotting, FACS, IHC, and functional studies.
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