Monoclonal Antibody to Arginase-1 (Clone: ABM4B35), Clone: [ABM4B35], Mouse
Artikelnummer:
ABI-10-7543
Hersteller Artikelnummer:
10-7543
Alternativnummer:
ABI-10-7543-100UG
Hersteller:
Abeomics
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
IHC, WB
Spezies Reaktivität:
Human
Immunogen:
A partial length recombinant Arginase-1 protein (amino acids 11-230) was used as the immunogen for this antibody
Alternative Synonym:
ARG1
Arginase-1 (Arg-1) is a binuclear manganese metalloenzyme that catalyzes the hydrolysis of arginine to ornithine and urea. It is expressed in normal human liver with a high degree of specificity, concentrated in periportal hepatocytes. Arginase-1 are urea cycle enzymes used to distinguish hepatocellular carcinoma from other carcinomas. Two transcript variants encoding different isoforms have been found for this gene. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.
