Monoclonal Antibody to Arginase-1 (Clone: ABM4B35), Clone: [ABM4B35], Mouse
Biozol Catalog Number:
ABI-10-7543
Supplier Catalog Number:
10-7543
Alternative Catalog Number:
ABI-10-7543-100UG
Manufacturer:
Abeomics
Host:
Mouse
Category:
Antikörper
Application:
IHC, WB
Species Reactivity:
Human
Immunogen:
A partial length recombinant Arginase-1 protein (amino acids 11-230) was used as the immunogen for this antibody
Alternative Names:
ARG1
Arginase-1 (Arg-1) is a binuclear manganese metalloenzyme that catalyzes the hydrolysis of arginine to ornithine and urea. It is expressed in normal human liver with a high degree of specificity, concentrated in periportal hepatocytes. Arginase-1 are urea cycle enzymes used to distinguish hepatocellular carcinoma from other carcinomas. Two transcript variants encoding different isoforms have been found for this gene. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.
