Monoclonal Antibody to Mouse PD-1 (Clone: ABM5F42), Clone: [ABM5F42], Unconjugated, Rat

Produktübersicht

• Artikelname: Monoclonal Antibody to Mouse PD-1 (Clone: ABM5F42), Clone: [ABM5F42], Unconjugated, Rat
• Artikelnummer: ABI-10-7612
• Hersteller Artikelnummer: 10-7612
• Alternativnummer: ABI-10-7612-100UG
• Hersteller: Abeomics
• Wirt: Rat
• Kategorie: Antikörper
• Applikation: FACS
• Spezies Reaktivität: Mouse
• Immunogen: partial length recombinant protein (a.a 07-211) of mPD-1 was used as the immunogen for this antibody.
• Konjugation: Unconjugated
• Alternative Synonym: Programmed cell death protein 1, Protein PD-1, CD279

Produktbeschreibung

PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [ABM5F42]
• NCBI: 18566
• UniProt: Q02242
• Reinheit: Protein G Chromatography
• Formulierung: Purified
• Target-Kategorie: mPD-1
• Antibody Type: Monoclonal Antibody

Anwendungsbeschreibung

• Application Verdünnung: FACS: 0.5-1 µg/10 6

Bilder

Fig:1- Cell surface flow analysis of mPD-1 in Con A treated Mouse Splenocytes using 0.5 µg/10 6 cells of mPD-1 antibody (Clone: ABM5F42). Green represents isotype control, red represents anti-mPD-1 antibody. Goat anti-rat PE conjugate was used as secondary antibody.