Monoclonal Antibody to Mouse PD-1 (Clone: ABM5F42), Clone: [ABM5F42], Unconjugated, Rat
Biozol Catalog Number:
ABI-10-7612
Supplier Catalog Number:
10-7612
Alternative Catalog Number:
ABI-10-7612-100UG
Manufacturer:
Abeomics
Host:
Rat
Category:
Antikörper
Application:
FACS
Species Reactivity:
Mouse
Immunogen:
partial length recombinant protein (a.a 07-211) of mPD-1 was used as the immunogen for this antibody.
Conjugation:
Unconjugated
Alternative Names:
Programmed cell death protein 1, Protein PD-1, CD279
PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
Fig:1- Cell surface flow analysis of mPD-1 in Con A treated Mouse Splenocytes using 0.5 µg/10 6 cells of mPD-1 antibody (Clone: ABM5F42). Green represents isotype control, red represents anti-mPD-1 antibody. Goat anti-rat PE conjugate was used as secondary antibody.
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