NFAT Leeportera Luciferase Reporter-Jurkat Cell Line Preis auf Anfrage

Produktübersicht

• Artikelname: NFAT Leeportera Luciferase Reporter-Jurkat Cell Line Preis auf Anfrage
• Artikelnummer: ABI-14-150ACL
• Hersteller Artikelnummer: 14-150ACL
• Alternativnummer: ABI-14-150ACL-1VIAL
• Hersteller: Abeomics
• Kategorie: Zellen/Zellkultur
• Applikation: FA

Produktbeschreibung

The NFAT Leeportera Luciferase Reporter cell line is a stably transfected Jurkat T cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the Nuclear Factor of Activated T-cells (NFAT) response element, so that the cell line is designed to measure the transcriptional activity of NFAT. NFAT is a transcription factor originally found in activated T lymphocytes, and is now known to regulate not only T cell activation and differentiation but also the function of other immune cells including dendritic cells, B cells and megakaryocytes. The NFAT induction by anti-CD3 antibody and ionomycin is shown in Figures 1 through 4.

Anwendungsbeschreibung

• Application Verdünnung: Application: Monitor the NFAT signaling pathway activity. Screen for activators or inhibitors of the NFAT signaling pathway. Culture conditions: Cells should be grown at 37oC with 5% CO2 using RPMI medium supplemented with 10% heat-inactivated FBS, 1 mM s