NFAT Leeportera Luciferase Reporter-Jurkat Cell Line Preis auf Anfrage
Biozol Catalog Number:
ABI-14-150ACL
Supplier Catalog Number:
14-150ACL
Alternative Catalog Number:
ABI-14-150ACL-1VIAL
Manufacturer:
Abeomics
Category:
Zellen/Zellkultur
Application:
FA
The NFAT Leeportera Luciferase Reporter cell line is a stably transfected Jurkat T cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the Nuclear Factor of Activated T-cells (NFAT) response element, so that the cell line is designed to measure the transcriptional activity of NFAT. NFAT is a transcription factor originally found in activated T lymphocytes, and is now known to regulate not only T cell activation and differentiation but also the function of other immune cells including dendritic cells, B cells and megakaryocytes. The NFAT induction by anti-CD3 antibody and ionomycin is shown in Figures 1 through 4.
Application Dilute:
Application: Monitor the NFAT signaling pathway activity. Screen for activators or inhibitors of the NFAT signaling pathway. Culture conditions: Cells should be grown at 37oC with 5% CO2 using RPMI medium supplemented with 10% heat-inactivated FBS, 1 mM s
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