Recombinant Human TWEAK Receptor/TWEAK R/TNFRSF12A (C-Fc)

Artikelnummer: ABI-32-9676-500
Artikelname: Recombinant Human TWEAK Receptor/TWEAK R/TNFRSF12A (C-Fc)
Artikelnummer: ABI-32-9676-500
Hersteller Artikelnummer: 32-9676-500
Alternativnummer: ABI-32-9676-500-500UG
Hersteller: Abeomics
Kategorie: Proteine/Peptide
Alternative Synonym: TNFRSF12A,Fibroblast growth factor-inducible immediate-early response protein 14, FN14, CD266 antigen and tweak-receptor.
Source : Human Cells,Tumor necrosis factor receptor superfamily member 12A(TNFRSF12A) is also known as Fibroblast growth factor-inducible immediate-early response protein 14, FN14, CD266 antigen and tweak-receptor. TNFRSF12A is a single-pass type I membrane protein, including a 27 aa signal peptide, a 53 aa extracellular domain, a 21 aa transmembrane domain and a 28 aa cytoplasmic domain. TNFRSF12A is highly expressed in heart, placenta and kidney. TNFRSF12A can be induced by FGF1 and phorbol ester. TNFRSF12A binds to TWEAK/TNFSF12A to initiate a signal transduction cascade, causing different cellular responses such as cell death, cell proliferation, and angiogenesis.
Antibody Type: Recombinant Antibody