Recombinant Human TWEAK Receptor/TWEAK R/TNFRSF12A (C-Fc)
Biozol Catalog Number:
ABI-32-9676-500
Supplier Catalog Number:
32-9676-500
Alternative Catalog Number:
ABI-32-9676-500-500UG
Manufacturer:
Abeomics
Category:
Proteine/Peptide
Alternative Names:
TNFRSF12A,Fibroblast growth factor-inducible immediate-early response protein 14, FN14, CD266 antigen and tweak-receptor.
Source : Human Cells,Tumor necrosis factor receptor superfamily member 12A(TNFRSF12A) is also known as Fibroblast growth factor-inducible immediate-early response protein 14, FN14, CD266 antigen and tweak-receptor. TNFRSF12A is a single-pass type I membrane protein, including a 27 aa signal peptide, a 53 aa extracellular domain, a 21 aa transmembrane domain and a 28 aa cytoplasmic domain. TNFRSF12A is highly expressed in heart, placenta and kidney. TNFRSF12A can be induced by FGF1 and phorbol ester. TNFRSF12A binds to TWEAK/TNFSF12A to initiate a signal transduction cascade, causing different cellular responses such as cell death, cell proliferation, and angiogenesis.
Antibody Type:
Recombinant Antibody
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