Anti-PD1, Mouse Monoclonal Antibody(Clone: RMP1-14), Clone: [RMP1-14], Rat

Produktübersicht

• Artikelname: Anti-PD1, Mouse Monoclonal Antibody(Clone: RMP1-14), Clone: [RMP1-14], Rat
• Artikelnummer: ABI-36-3818
• Hersteller Artikelnummer: 36-3818
• Alternativnummer: ABI-36-3818-100UG
• Hersteller: Abeomics
• Wirt: Rat
• Kategorie: Antikörper
• Applikation: ELISA, FACS, IF
• Spezies Reaktivität: Mouse
• Immunogen: PDCD1 transfected BHK cells
• Alternative Synonym: CD279, CD279 antigen, PD1, PDCD1, Programmed cell death 1, Programmed cell death protein 1, Systemic lupus erythematosus susceptibility 2 (SLEB2)

Produktbeschreibung

PD-1 is expressed on a subset of CD4-CD8-thymocytes, and on activated T and B cells. PD-1 is thoµght to be involved in lymphocyte clonal selection and peripheral tolerance. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. PD-1 is transiently expressed on CD4 and CD8 thymocytes as well as activated T and B-lymphocytes and myeloid cells. Additionally,Pdcd1mRNA is expressed in developing B-lymphocytes during the pro-B-cell stage. The RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production co-stimulated by macrophages (but not by dendritic cells and B cells).

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [RMP1-14]
• NCBI: 18566
• UniProt: Q02242

Anwendungsbeschreibung

• Application Verdünnung: ELISA (For coating, order Ab without BSA & Azide), Neutralization Studies (Order Ab without BSA & Azide), Flow Cytometry (1-2ug/million cells), Immunofluorescence (1-2ug/ml),