Anti-PD1, Mouse Monoclonal Antibody(Clone: RMP1-14), Clone: [RMP1-14], Rat
Biozol Catalog Number:
ABI-36-3818
Supplier Catalog Number:
36-3818
Alternative Catalog Number:
ABI-36-3818-100UG
Manufacturer:
Abeomics
Host:
Rat
Category:
Antikörper
Application:
ELISA, FACS, IF
Species Reactivity:
Mouse
Immunogen:
PDCD1 transfected BHK cells
Alternative Names:
CD279, CD279 antigen, PD1, PDCD1, Programmed cell death 1, Programmed cell death protein 1, Systemic lupus erythematosus susceptibility 2 (SLEB2)
PD-1 is expressed on a subset of CD4-CD8-thymocytes, and on activated T and B cells. PD-1 is thoµght to be involved in lymphocyte clonal selection and peripheral tolerance. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. PD-1 is transiently expressed on CD4 and CD8 thymocytes as well as activated T and B-lymphocytes and myeloid cells. Additionally,Pdcd1mRNA is expressed in developing B-lymphocytes during the pro-B-cell stage. The RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production co-stimulated by macrophages (but not by dendritic cells and B cells).
ELISA (For coating, order Ab without BSA & Azide), Neutralization Studies (Order Ab without BSA & Azide), Flow Cytometry (1-2ug/million cells), Immunofluorescence (1-2ug/ml),
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