Anti-PKB alpha Monoclonal Antibody (Clone: PKB-175), Clone: [PKB-175], Mouse

Produktübersicht

• Artikelname: Anti-PKB alpha Monoclonal Antibody (Clone: PKB-175), Clone: [PKB-175], Mouse
• Artikelnummer: ABI-39-1088
• Hersteller Artikelnummer: 39-1088
• Alternativnummer: ABI-39-1088-100UG/VIAL
• Hersteller: Abeomics
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide corresponding to amino acids 461-477 of human PKB alpha/Akt1, conjugated to KLH.
• Alternative Synonym: RAC-alpha serine/threonine-protein kinase, 2.7.11.1, Protein kinase B, PKB, Protein kinase B alpha, PKB alpha, RAC-PK-alpha, Akt1

Produktbeschreibung

PKB alpha also knows as V-AKT murine thymoma vial oncogene homolog 1(ATK1). AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and is abrogated by mutations in the pleckstrin homology domain of AKT1. AKT1 gene is mapped to chromosome 14q32.3. Akt1/protein kinase B-alpha is critical for ischemic and VEGF-mediated angiogenesis. Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [PKB-175]
• NCBI: 24185
• UniProt: P47196
• Reinheit: Ascites
• Target-Kategorie: RAC-alpha serine/threonine-protein kinase
• Antibody Type: Monoclonal Antibody

Anwendungsbeschreibung

• Application Verdünnung: Western blot : 0.25-0.5µg/ml

Bilder

Figure 1: Anti-PKB alpha antibody 39-1088. Western blotting: Lanes: Anti PKB alpha(39-1088) at 0.5ug/ml, Lane 1: Rat Ovary Tissue Lysate at 50ug, Lane 2: PC-12 Whole Cell Lysate at 40ug, Lane 3: A549 Whole Cell Lysate at 40ug, Lane 4: MCF-7 Whole Cell Lysate at 40ug, Lane 5: HEPA Whole Cell Lysate at 40ug. Predicted band size: 56 kDa. Observed band size: 56 kDa.