Anti-PKB alpha Monoclonal Antibody (Clone: PKB-175), Clone: [PKB-175], Mouse

Product Overview

• Article Name: Anti-PKB alpha Monoclonal Antibody (Clone: PKB-175), Clone: [PKB-175], Mouse
• Biozol Catalog Number: ABI-39-1088
• Supplier Catalog Number: 39-1088
• Alternative Catalog Number: ABI-39-1088-100UG/VIAL
• Manufacturer: Abeomics
• Host: Mouse
• Category: Antikörper
• Application: WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide corresponding to amino acids 461-477 of human PKB alpha/Akt1, conjugated to KLH.
• Alternative Names: RAC-alpha serine/threonine-protein kinase, 2.7.11.1, Protein kinase B, PKB, Protein kinase B alpha, PKB alpha, RAC-PK-alpha, Akt1

Product Description

PKB alpha also knows as V-AKT murine thymoma vial oncogene homolog 1(ATK1). AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and is abrogated by mutations in the pleckstrin homology domain of AKT1. AKT1 gene is mapped to chromosome 14q32.3. Akt1/protein kinase B-alpha is critical for ischemic and VEGF-mediated angiogenesis. Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [PKB-175]
• NCBI: 24185
• UniProt: P47196
• Purity: Ascites
• Target: RAC-alpha serine/threonine-protein kinase
• Antibody Type: Monoclonal Antibody

Application Notes

• Application Dilute: Western blot : 0.25-0.5µg/ml

Images

Figure 1: Anti-PKB alpha antibody 39-1088. Western blotting: Lanes: Anti PKB alpha(39-1088) at 0.5ug/ml, Lane 1: Rat Ovary Tissue Lysate at 50ug, Lane 2: PC-12 Whole Cell Lysate at 40ug, Lane 3: A549 Whole Cell Lysate at 40ug, Lane 4: MCF-7 Whole Cell Lysate at 40ug, Lane 5: HEPA Whole Cell Lysate at 40ug. Predicted band size: 56 kDa. Observed band size: 56 kDa.