Anti-BSEP Monoclonal Antibody (Clone:IHC518)-Ready to Use, Clone: [IHC518], Mouse
Artikelnummer:
ABI-44-1007
Hersteller Artikelnummer:
44-1007
Alternativnummer:
ABI-44-1007-7ML
Hersteller:
Abeomics
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
IHC
Spezies Reaktivität:
Human
Immunogen:
Recombinant Human BSEP
Alternative Synonym:
ABCB11||BSEP
Bile Salt Export Pump (BSEP) is a member of the ATP-binding cassette (ABC) transporters, which mediates the transport of bile acid, taurocholate and other cholate conjugates across the hepatocyte canalicular membrane into the canaliculus. BSEP is associated with progressive familial intrahepatic cholestasis type 2 (PFIC2) and benign recurrent intrahepatic cholestasis type 2 (BRIC2). PFIC2 caused by mutations in the BSEP gene increases the risk of hepatocellular carcinoma in early life.