Anti-BSEP Monoclonal Antibody (Clone:IHC518)-Ready to Use, Clone: [IHC518], Mouse
Biozol Catalog Number:
ABI-44-1007
Supplier Catalog Number:
44-1007
Alternative Catalog Number:
ABI-44-1007-7ML
Manufacturer:
Abeomics
Host:
Mouse
Category:
Antikörper
Application:
IHC
Species Reactivity:
Human
Immunogen:
Recombinant Human BSEP
Alternative Names:
ABCB11||BSEP
Bile Salt Export Pump (BSEP) is a member of the ATP-binding cassette (ABC) transporters, which mediates the transport of bile acid, taurocholate and other cholate conjugates across the hepatocyte canalicular membrane into the canaliculus. BSEP is associated with progressive familial intrahepatic cholestasis type 2 (PFIC2) and benign recurrent intrahepatic cholestasis type 2 (BRIC2). PFIC2 caused by mutations in the BSEP gene increases the risk of hepatocellular carcinoma in early life.