Anti-PAX-8 Monoclonal Antibody (Clone:IHC008)-Ready to Use, Clone: [IHC008], Mouse
Artikelnummer:
ABI-44-1066
Hersteller Artikelnummer:
44-1066
Alternativnummer:
ABI-44-1066-7ML
Hersteller:
Abeomics
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
IHC
Spezies Reaktivität:
Human
Immunogen:
Recombinant Human PAX8
Alternative Synonym:
PAX8
PAX-8 is a member of the paired box (PAX) family of transcription factors, which are key regulators in early development. This protein plays a role in development of thyroid follicular cells and the expression of thyroid-specific genes, with mutations in the PAX-8 gene linked to thyroid follicular carcinomas, atypical thyroid adenomas, and thyroid dysgenesis. The PAX-8 protein is expressed in simple ovarian inclusion cysts and non-ciliated mucosal cells of the fallopian tubes, but is absent from normal ovarian surface epithelial cells. PAX-8 is also not expressed in normal lung or lung carcinomas.