Anti-PAX-8 Monoclonal Antibody (Clone:IHC008)-Ready to Use, Clone: [IHC008], Mouse
Biozol Catalog Number:
ABI-44-1066
Supplier Catalog Number:
44-1066
Alternative Catalog Number:
ABI-44-1066-7ML
Manufacturer:
Abeomics
Host:
Mouse
Category:
Antikörper
Application:
IHC
Species Reactivity:
Human
Immunogen:
Recombinant Human PAX8
Alternative Names:
PAX8
PAX-8 is a member of the paired box (PAX) family of transcription factors, which are key regulators in early development. This protein plays a role in development of thyroid follicular cells and the expression of thyroid-specific genes, with mutations in the PAX-8 gene linked to thyroid follicular carcinomas, atypical thyroid adenomas, and thyroid dysgenesis. The PAX-8 protein is expressed in simple ovarian inclusion cysts and non-ciliated mucosal cells of the fallopian tubes, but is absent from normal ovarian surface epithelial cells. PAX-8 is also not expressed in normal lung or lung carcinomas.