Anti-CD45R Monoclonal Antibody (Clone:IHC536)-Ready to Use, Clone: [IHC536], Mouse
Artikelnummer:
ABI-44-1132
Hersteller Artikelnummer:
44-1132
Alternativnummer:
ABI-44-1132-7ML
Hersteller:
Abeomics
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
IHC
Spezies Reaktivität:
Human
Alternative Synonym:
Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, CD45, L-CA, T200
CD45R, also known as MB1, is an isoform of CD45 that is a member of the protein tyrosine phosphatase (PTPase) family. CD45R is expressed specifically on the surface of hematopoietic cells, and has demonstrated function as a regulator of the antigen and cytokine receptor signalling of B and T cells. Given that the antigen is located in the membrane of all B cells, with the exception of plasma cells and some mature T cells, Anti-CD45R exhibits specific reactivity with most B lymphocytes. The use of Anti-CD45R is primarily useful in distinguishing B cell lymphomas from T cell lymphomas, with specific reactivity to follicle center cells, mantle cells, some medullary thymocytes, and 80% of B cell lymphomas.
