Anti-CD45R Monoclonal Antibody (Clone:IHC536)-Ready to Use, Clone: [IHC536], Mouse
Biozol Catalog Number:
ABI-44-1132
Supplier Catalog Number:
44-1132
Alternative Catalog Number:
ABI-44-1132-7ML
Manufacturer:
Abeomics
Host:
Mouse
Category:
Antikörper
Application:
IHC
Species Reactivity:
Human
Alternative Names:
Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, CD45, L-CA, T200
CD45R, also known as MB1, is an isoform of CD45 that is a member of the protein tyrosine phosphatase (PTPase) family. CD45R is expressed specifically on the surface of hematopoietic cells, and has demonstrated function as a regulator of the antigen and cytokine receptor signalling of B and T cells. Given that the antigen is located in the membrane of all B cells, with the exception of plasma cells and some mature T cells, Anti-CD45R exhibits specific reactivity with most B lymphocytes. The use of Anti-CD45R is primarily useful in distinguishing B cell lymphomas from T cell lymphomas, with specific reactivity to follicle center cells, mantle cells, some medullary thymocytes, and 80% of B cell lymphomas.
