Human B7-H2 / ICOSLG Protein, Fc Tag, Unconjugated

Produktübersicht

• Artikelname: Human B7-H2 / ICOSLG Protein, Fc Tag, Unconjugated
• Artikelnummer: ABS-B72-H5254-100UG
• Hersteller Artikelnummer: B72-H5254-100ug
• Alternativnummer: ABS-B72-H5254-100UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

ICOS ligand (ICOSLG) is also known as B7 homolog 2 (B7H2), B7related protein 1 (B7RP1) and CD antigen CD275, which belongs to the immunoglobulin superfamily and BTN/MOG family. ICOSLG contains one Iglike C2type (immunoglobulinlike) domain and one Iglike Vtype (immunoglobulinlike) domain. Isoform 1 is widely expressed, while isoform 2 is detected only in lymph nodes, leukocytes and spleen. B7H2 is ligand for the Tcellspecific cell surface receptor ICOS. B7H2 acts as a costimulatory signal for Tcell proliferation and cytokine secretion and induces also Bcell proliferation and differentiation into plasma cells. B7H2 could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by costimulating memory Tcell function. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 53.1 kDa
• Tag: C-Fc
• NCBI: 75144
• Puffer: Tris with Glycine, Arginine and NaCl, pH7.5
• Reinheit: 95%
• Formulierung: Powder
• Target-Kategorie: B7-H2

Bilder

Immobilized Human ICOS (C136S, C137S), His Tag at 5 µg/mL (100 µL/well) can bind Human B7-H2, Fc Tag (Cat. No. B72-H5254) with a linear range of 0.3-5 ng/mL (QC tested).

B72-H5254-100ug

Human B7-H2, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.