Human CD38 Protein, Fc Tag (MALS verified), Unconjugated
Artikelnummer:
ABS-CD8-H5255-1MG
Hersteller Artikelnummer:
CD8-H5255-1mg
Alternativnummer:
ABS-CD8-H5255-1MG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
CD antigen CD38 is also known as ADPribosyl cyclase 1, which belongs to the ADPribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADPribose (cADPR) from NAD+ to ADPribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia. - Proteine/Peptide
