Human CD38 Protein, Fc Tag (MALS verified), Unconjugated
Biozol Catalog Number:
ABS-CD8-H5255-1MG
Supplier Catalog Number:
CD8-H5255-1mg
Alternative Catalog Number:
ABS-CD8-H5255-1MG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
CD antigen CD38 is also known as ADPribosyl cyclase 1, which belongs to the ADPribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADPribose (cADPR) from NAD+ to ADPribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia. - Proteine/Peptide
