FITC-Labeled Human CD27 Ligand / CD70 Protein, His,Flag Tag, active trimer (MALS verified)
Artikelnummer:
ABS-CDD-HF2D4-200UG
Hersteller Artikelnummer:
CDD-HF2D4-200ug
Alternativnummer:
ABS-CDD-HF2D4-200UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
FITC
Cluster of Differentiation 70 (CD70) is also known as CD27 ligand (CD27L / CD27LG), TNFSF7, TNFSF7G, is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and is a surface antigen found on activated Tand Blymphocytes and mature dendritic cells. Binding of CD70 to its receptor CD27 induces in priming, effector functions, differentiation and memory formation of Tcells, and thus is invloved in the biological processes including Tcell activation, the proliferation of costimulated Tcells, as well as the generation of cytolytic Tcells. CD70 on T cells provides costimulatory signals that are required for T cell proliferation, clonal expansion and the promotion of effector T cell formation. CD70 on mouse B cell has been shown to inhibit terminal differentiation of activated B cells into plasma cells and enhances commitment to memory B cell responses. CD70 induces proliferation and IFNgamma production, on NK cells. - Proteine/Peptide
Immobilized Anti-CD27 Ligand Antibody, Human IgG1 at 1 µg/mL (100 µL/well) can bind FITC-Labeled Human CD27 Ligand, His,Flag Tag (Cat. No. CDD-HF2D4) with a linear range of 0.039-0.156 µg/mL (QC tested).
Immobilized Human CD27, Fc Tag (Cat. No. CD7-H5254) at 5 µg/mL (100 µL/well) can bind FITC-Labeled Human CD27 Ligand, His,Flag Tag (Cat. No. CDD-HF2D4) with a linear range of 0.039-0.156 µg/mL (Routinely tested).
FITC-Labeled Human CD27 Ligand, His,Flag Tag on SDS-PAGE under non-reducing (NR) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
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