FITC-Labeled Human CD27 Ligand / CD70 Protein, His,Flag Tag, active trimer (MALS verified)

Catalog Number: ABS-CDD-HF2D4-200UG
Article Name: FITC-Labeled Human CD27 Ligand / CD70 Protein, His,Flag Tag, active trimer (MALS verified)
Biozol Catalog Number: ABS-CDD-HF2D4-200UG
Supplier Catalog Number: CDD-HF2D4-200ug
Alternative Catalog Number: ABS-CDD-HF2D4-200UG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Conjugation: FITC
Cluster of Differentiation 70 (CD70) is also known as CD27 ligand (CD27L / CD27LG), TNFSF7, TNFSF7G, is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and is a surface antigen found on activated Tand Blymphocytes and mature dendritic cells. Binding of CD70 to its receptor CD27 induces in priming, effector functions, differentiation and memory formation of Tcells, and thus is invloved in the biological processes including Tcell activation, the proliferation of costimulated Tcells, as well as the generation of cytolytic Tcells. CD70 on T cells provides costimulatory signals that are required for T cell proliferation, clonal expansion and the promotion of effector T cell formation. CD70 on mouse B cell has been shown to inhibit terminal differentiation of activated B cells into plasma cells and enhances commitment to memory B cell responses. CD70 induces proliferation and IFNgamma production, on NK cells. - Proteine/Peptide
Molecular Weight: 49.3 kDa
Tag: N-6*His & N-Flag
NCBI: 32970
Buffer: PBS, pH7.4
Purity: 90%
Form: Powder
Target: CD27 Ligand
Immobilized Anti-CD27 Ligand Antibody, Human IgG1 at 1 µg/mL (100 µL/well) can bind FITC-Labeled Human CD27 Ligand, His,Flag Tag (Cat. No. CDD-HF2D4) with a linear range of 0.039-0.156 µg/mL (QC tested).
Immobilized Human CD27, Fc Tag (Cat. No. CD7-H5254) at 5 µg/mL (100 µL/well) can bind FITC-Labeled Human CD27 Ligand, His,Flag Tag (Cat. No. CDD-HF2D4) with a linear range of 0.039-0.156 µg/mL (Routinely tested).
FITC-Labeled Human CD27 Ligand, His,Flag Tag on SDS-PAGE under non-reducing (NR) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.