HEK293/Human Claudin-18.2 Stable Cell Line 2 Vials Preis auf Anfrage

Produktübersicht

• Artikelname: HEK293/Human Claudin-18.2 Stable Cell Line 2 Vials Preis auf Anfrage
• Artikelnummer: ABS-CHEK-ATP033-2VIALS
• Hersteller Artikelnummer: CHEK-ATP033-2Vials
• Alternativnummer: ABS-CHEK-ATP033-2VIALS
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Zellen/Zellkultur
• Spezies Reaktivität: Human

Produktbeschreibung

Claudins (CLDNs) are a family of proteins that form tight junctions and maintain the polarity of epithelial and endothelial cells. CLDN18 is specifically expressed in the stomach and lung. Of the two CLDN18 isoform transcripts produced by alternative splicing, CLDN18.2 is a highly selective gastric lineage marker that determines the gastric phenotype in a neoplastic condition, whereas CLDN18.1 is lung specific. CLDN18.2 is a highly selective gastric lineage antigen expressed exclusively on shortlived differentiated gastric epithelial cells where it has only limited accessibility to antibody drugs.14,15 CLDN18.2 is maintained during the course of malignant transformation and thus frequently displayed on the surface of human gastric cancer cells. - Zellen/Zellkultur

Produkteigenschaften

• Formulierung: Liquid
• Target-Kategorie: Claudin-18.2

Anwendungsbeschreibung

• Anwendungsbeschreibung: Binding assay by FACS and cell based ELISA.

Bilder

CHEK-ATP033-2Vials