HEK293/Human Claudin-18.2 Stable Cell Line 2 Vials Preis auf Anfrage
Biozol Catalog Number:
ABS-CHEK-ATP033-2VIALS
Supplier Catalog Number:
CHEK-ATP033-2Vials
Alternative Catalog Number:
ABS-CHEK-ATP033-2VIALS
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Zellen/Zellkultur
Species Reactivity:
Human
Claudins (CLDNs) are a family of proteins that form tight junctions and maintain the polarity of epithelial and endothelial cells. CLDN18 is specifically expressed in the stomach and lung. Of the two CLDN18 isoform transcripts produced by alternative splicing, CLDN18.2 is a highly selective gastric lineage marker that determines the gastric phenotype in a neoplastic condition, whereas CLDN18.1 is lung specific. CLDN18.2 is a highly selective gastric lineage antigen expressed exclusively on shortlived differentiated gastric epithelial cells where it has only limited accessibility to antibody drugs.14,15 CLDN18.2 is maintained during the course of malignant transformation and thus frequently displayed on the surface of human gastric cancer cells. - Zellen/Zellkultur
Form:
Liquid
Target:
Claudin-18.2
Application Notes:
Binding assay by FACS and cell based ELISA.
CHEK-ATP033-2Vials
* VAT and and shipping costs not included. Errors and price changes excepted
