HEK293/Human APP (GFP) Stable Cell Line 2 Vials Preis auf Anfrage
Artikelnummer:
ABS-CHEK-ATP081-2VIALS
Hersteller Artikelnummer:
CHEK-ATP081-2Vials
Alternativnummer:
ABS-CHEK-ATP081-2VIALS
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Zellen/Zellkultur
Spezies Reaktivität:
Human
Amyloid precursor protein (APP) is a type I integral membrane protein ubiquitously expressed in many tissues and concentrated in the synapses of neurons. The majority of APP is cleaved at the plasma membrane by the alphasecretase in the nonamyloidogenic pathway. The amyloidogenic pathway starts with betasecretase cleavage by BACE1 on the Nterminal part of the Abeta domain, releasing sAPPbeta from a membraneanchored fragment named betaCTF or C103, which is subsequently cleaved by gammasecretase to release Abeta. - Zellen/Zellkultur
Tag:
GFP Tag
Formulierung:
Liquid
Target-Kategorie:
APP
Anwendungsbeschreibung:
Screening beta-secretase and gamma-secretase inhibitors which stops Abeta peptide formation.
CHEK-ATP081-2Vials
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten