HEK293/Human APP (GFP) Stable Cell Line 2 Vials Preis auf Anfrage

Catalog Number: ABS-CHEK-ATP081-2VIALS
Article Name: HEK293/Human APP (GFP) Stable Cell Line 2 Vials Preis auf Anfrage
Biozol Catalog Number: ABS-CHEK-ATP081-2VIALS
Supplier Catalog Number: CHEK-ATP081-2Vials
Alternative Catalog Number: ABS-CHEK-ATP081-2VIALS
Manufacturer: AcroBiosystems
Host: Human
Category: Zellen/Zellkultur
Species Reactivity: Human
Amyloid precursor protein (APP) is a type I integral membrane protein ubiquitously expressed in many tissues and concentrated in the synapses of neurons. The majority of APP is cleaved at the plasma membrane by the alphasecretase in the nonamyloidogenic pathway. The amyloidogenic pathway starts with betasecretase cleavage by BACE1 on the Nterminal part of the Abeta domain, releasing sAPPbeta from a membraneanchored fragment named betaCTF or C103, which is subsequently cleaved by gammasecretase to release Abeta. - Zellen/Zellkultur
Tag: GFP Tag
Form: Liquid
Target: APP
Application Notes: Screening beta-secretase and gamma-secretase inhibitors which stops Abeta peptide formation.
CHEK-ATP081-2Vials