Cynomolgus CRTAM Protein, Fc Tag, Unconjugated, Human

Produktübersicht

• Artikelname: Cynomolgus CRTAM Protein, Fc Tag, Unconjugated, Human
• Artikelnummer: ABS-CRM-C5255-100UG
• Hersteller Artikelnummer: CRM-C5255-100ug
• Alternativnummer: ABS-CRM-C5255-100UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Monkey
• Konjugation: Unconjugated

Produktbeschreibung

Class Irestricted T cellassociated molecule (CRTAM), a member of nectin family and the immunoglobulin superfamily, is also known as cytotoxic and regulatory Tcell molecule, which is expressed by activated CD8+ and NK T cells. CRTAM is found in spleen, thymus, small intestine, peripheral blood, and surprisingly, in brain where it is highly expressed by Purkinje cells of the cerebellum. The high affinity of CRTAM/IGSF4 adhesion allows CRTAM to disrupt IGSF4 homotypic interactions (3 5). IGSF4 and T cell receptor coengagement of CRTAMexpressing CD8+ cells induces increased IFNgamma or IL22 production (3, 4). Furthermore, a role in cancer surveillance through NK cellmediated rejection of IGSF4expressing tumors has been proposed. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 56.6 kDa
• Tag: C-Fc
• NCBI: 005580021
• Puffer: Tris with Glycine, Arginine and NaCl, pH7.5
• Reinheit: 95%
• Formulierung: Powder
• Target-Kategorie: CRTAM

Bilder

CRM-C5255-100ug

Immobilized Human CADM1, His Tag (Cat. No. CA1-H5225) at 5 µg/mL (100 µL/well) can bind Cynomolgus CRTAM, Fc Tag (Cat. No. CRM-C5255) with a linear range of 0.6-10 ng/mL (QC tested).

Cynomolgus CRTAM, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.