Human Cathepsin B / CTSB (L26V) Protein, Tag Free (active enzyme, MALS verified), Unconjugated 50 ug

Produktübersicht

• Artikelname: Human Cathepsin B / CTSB (L26V) Protein, Tag Free (active enzyme, MALS verified), Unconjugated 50 ug
• Artikelnummer: ABS-CTB-H5213-50UG
• Hersteller Artikelnummer: CTB-H5213-50ug
• Alternativnummer: ABS-CTB-H5213-50UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

Cathepsin B (CTSB) is also known as APP secretase (APPS) and CPSB, is an enzymatic protein belonging to the peptidase C1 family. Cathepsin B / CTSB is synthesized as a preproenzyme. Following removal of the signal peptide, the inactive proenzyme undergoes further modifications including removal of the pro region to result in the active enzyme. The catalytic activity of Cathepsin B / APPS contains: Hydrolysis of proteins with broad specificity for peptide bonds, Preferentially cleaves ArgArg|Xaa bonds in small molecule substrates (thus differing from cathepsin L), In addition to being an endopeptidase, shows peptidyldipeptidase activity, liberating Cterminal dipeptides. As a thiol protease, cathepsin B / CPSB is believed to participate in intracellular degradation and turnover of proteins and has also been implicated in tumor invasion and metastasis. Overexpression of cathepsin B has been associated with esophageal adenocarcinoma and other tumors. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 35.9 kDa
• Tag: Native
• NCBI: 07858
• Puffer: 20 mM NaAC, 0.2 M NaCl, pH4.8
• Reinheit: 90%
• Formulierung: Liquid
• Target-Kategorie: Cathepsin B

Bilder

Human Cathepsin B (L26V) Protein, Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.