Human Cathepsin B / CTSB (L26V) Protein, Tag Free (active enzyme, MALS verified), Unconjugated 50 ug

Product Overview

• Article Name: Human Cathepsin B / CTSB (L26V) Protein, Tag Free (active enzyme, MALS verified), Unconjugated 50 ug
• Biozol Catalog Number: ABS-CTB-H5213-50UG
• Supplier Catalog Number: CTB-H5213-50ug
• Alternative Catalog Number: ABS-CTB-H5213-50UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Cathepsin B (CTSB) is also known as APP secretase (APPS) and CPSB, is an enzymatic protein belonging to the peptidase C1 family. Cathepsin B / CTSB is synthesized as a preproenzyme. Following removal of the signal peptide, the inactive proenzyme undergoes further modifications including removal of the pro region to result in the active enzyme. The catalytic activity of Cathepsin B / APPS contains: Hydrolysis of proteins with broad specificity for peptide bonds, Preferentially cleaves ArgArg|Xaa bonds in small molecule substrates (thus differing from cathepsin L), In addition to being an endopeptidase, shows peptidyldipeptidase activity, liberating Cterminal dipeptides. As a thiol protease, cathepsin B / CPSB is believed to participate in intracellular degradation and turnover of proteins and has also been implicated in tumor invasion and metastasis. Overexpression of cathepsin B has been associated with esophageal adenocarcinoma and other tumors. - Proteine/Peptide

Product Properties

• Molecular Weight: 35.9 kDa
• Tag: Native
• NCBI: 07858
• Buffer: 20 mM NaAC, 0.2 M NaCl, pH4.8
• Purity: 90%
• Form: Liquid
• Target: Cathepsin B

Images

Human Cathepsin B (L26V) Protein, Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.