Human Erythropoietin R / EPO R Protein, His Tag (MALS & SPR verified), Unconjugated

Produktübersicht

• Artikelname: Human Erythropoietin R / EPO R Protein, His Tag (MALS & SPR verified), Unconjugated
• Artikelnummer: ABS-EPR-H52H4-1MG
• Hersteller Artikelnummer: EPR-H52H4-1mg
• Alternativnummer: ABS-EPR-H52H4-1MG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 26.7 kDa
• Tag: C-10*His
• NCBI: 19235
• Puffer: PBS, pH7.4
• Reinheit: 90%
• Formulierung: Powder
• Target-Kategorie: Erythropoietin R

Bilder

Human Erythropoietin R Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

EPR-H52H4-1mg

Immobilized Human Erythropoietin R Protein, His Tag (Cat. No. EPR-H52H4) at 5 µg/mL (100 µL/well) can bind Human Erythropoietin Protein, Fc Tag (Cat. No. EPO-H5253) with a linear range of 0.2-2 ng/mL (Routinely tested).