Human Erythropoietin R / EPO R Protein, His Tag (MALS & SPR verified), Unconjugated

Product Overview

• Article Name: Human Erythropoietin R / EPO R Protein, His Tag (MALS & SPR verified), Unconjugated
• Biozol Catalog Number: ABS-EPR-H52H4-1MG
• Supplier Catalog Number: EPR-H52H4-1mg
• Alternative Catalog Number: ABS-EPR-H52H4-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants. - Proteine/Peptide

Product Properties

• Molecular Weight: 26.7 kDa
• Tag: C-10*His
• NCBI: 19235
• Buffer: PBS, pH7.4
• Purity: 90%
• Form: Powder
• Target: Erythropoietin R

Images

Human Erythropoietin R Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

EPR-H52H4-1mg

Immobilized Human Erythropoietin R Protein, His Tag (Cat. No. EPR-H52H4) at 5 µg/mL (100 µL/well) can bind Human Erythropoietin Protein, Fc Tag (Cat. No. EPO-H5253) with a linear range of 0.2-2 ng/mL (Routinely tested).