Human FUS Protein, MBP,His Tag, Unconjugated, E. coli

Produktübersicht

• Artikelname: Human FUS Protein, MBP,His Tag, Unconjugated, E. coli
• Artikelnummer: ABS-FUS-H5144-100UG
• Hersteller Artikelnummer: FUS-H5144-100ug
• Alternativnummer: ABS-FUS-H5144-100UG
• Hersteller: AcroBiosystems
• Wirt: E. coli
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

FUS (RNAbinding protein FUS) is a DNA/RNAbinding protein that plays a role in various cellular processes such as transcription regulation, RNA splicing, RNA transport, DNA repair and damage response. It binds to nascent premRNAs and acts as a molecular mediator between RNA polymerase II and U1 small nuclear ribonucleoprotein thereby coupling transcription and splicing. It binds also its own premRNA and autoregulates its expression, this autoregulation mechanism is mediated by nonsensemediated decay. FUS plays a role in DNA repair mechanisms by promoting Dloop formation and homologous recombination during DNA doublestrand break repair. In neuronal cells, FUS plays crucial roles in dendritic spine formation and stability, RNA transport, mRNA stability and synaptic homeostasis. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 97.0 kDa
• Tag: N-MBP & N-10*His
• NCBI: 35637
• Puffer: PBS, pH7.4
• Reinheit: 85%
• Formulierung: Powder
• Target-Kategorie: FUS

Bilder

Immobilized Human FUS Protein, MBP,His Tag (Cat. No. FUS-H5144) at 1 µg/mL (100 µL/well) can bind FUS antibody, Mouse IgG with a linear range of 0.2-4 ng/mL (QC tested).

Human FUS Protein, MBP,His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 85%.