Rhesus macaque Coagulation factor XI Protein, His Tag (SPR verified), Unconjugated, Human
Artikelnummer:
ABS-FXI-C52H3-50UG
Hersteller Artikelnummer:
FXI-C52H3-50ug
Alternativnummer:
ABS-FXI-C52H3-50UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Monkey
Konjugation:
Unconjugated
This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality - Proteine/Peptide
Immobilized Rhesus macaque Coagulation factor XI Protein, His Tag (Cat. No. FXI-C52H3) at 1 µg/mL (100 µL/well) can bind Abelacimab with a linear range of 0.03-2 ng/mL (QC tested).
Immobilized Abelacimab at 1 µg/mL (100 µL/well) can bind Rhesus macaque Coagulation factor XI Protein, His Tag (Cat. No. FXI-C52H3) with a linear range of 0.001-0.063 µg/mL (Routinely tested).
Rhesus macaque Coagulation factor XI Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
FXI-C52H3-50ug
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