Rhesus macaque Coagulation factor XI Protein, His Tag (SPR verified), Unconjugated, Human

Product Overview

• Article Name: Rhesus macaque Coagulation factor XI Protein, His Tag (SPR verified), Unconjugated, Human
• Biozol Catalog Number: ABS-FXI-C52H3-50UG
• Supplier Catalog Number: FXI-C52H3-50ug
• Alternative Catalog Number: ABS-FXI-C52H3-50UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Monkey
• Conjugation: Unconjugated

Product Description

This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality - Proteine/Peptide

Product Properties

• Molecular Weight: 69.8 kDa
• Tag: C-10*His
• NCBI: 7
• Buffer: 20 mM HEPES,150 mM NaCl,pH7.5
• Purity: 90%
• Form: Powder
• Target: Coagulation factor XI

Images

Immobilized Rhesus macaque Coagulation factor XI Protein, His Tag (Cat. No. FXI-C52H3) at 1 µg/mL (100 µL/well) can bind Abelacimab with a linear range of 0.03-2 ng/mL (QC tested).

Immobilized Abelacimab at 1 µg/mL (100 µL/well) can bind Rhesus macaque Coagulation factor XI Protein, His Tag (Cat. No. FXI-C52H3) with a linear range of 0.001-0.063 µg/mL (Routinely tested).

Rhesus macaque Coagulation factor XI Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

FXI-C52H3-50ug