Human Frizzled-5 / FZD5 Protein, Fc Tag, Unconjugated
Artikelnummer:
ABS-FZ5-H5259-100UG
Hersteller Artikelnummer:
FZ5-H5259-100ug
Alternativnummer:
ABS-FZ5-H5259-100UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Frizzled5 (FZD5) is also known as FzE5, which belongs to the Gprotein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the betacatenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK3 kinase, nuclear accumulation of betacatenin and activation of Wnt target genes. FZD5 contains one FZ (frizzled) domain. FZD5 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD5 interacts specifically with Wnt5A to induce the betacatenin pathway. FZD5 interacts with GOPC. - Proteine/Peptide
