Human Frizzled-5 / FZD5 Protein, Fc Tag, Unconjugated

Product Overview

• Article Name: Human Frizzled-5 / FZD5 Protein, Fc Tag, Unconjugated
• Biozol Catalog Number: ABS-FZ5-H5259-100UG
• Supplier Catalog Number: FZ5-H5259-100ug
• Alternative Catalog Number: ABS-FZ5-H5259-100UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Frizzled5 (FZD5) is also known as FzE5, which belongs to the Gprotein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the betacatenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK3 kinase, nuclear accumulation of betacatenin and activation of Wnt target genes. FZD5 contains one FZ (frizzled) domain. FZD5 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD5 interacts specifically with Wnt5A to induce the betacatenin pathway. FZD5 interacts with GOPC. - Proteine/Peptide

Product Properties

• Molecular Weight: 42.6 kDa
• Tag: C-Fc
• NCBI: 13467
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Powder
• Target: Frizzled-5

Images

Immobilized Human Frizzled-5, Fc Tag (Cat. No. FZ5-H5259) at 1 µg/mL (100 µL/well) can bind Wnt surrogate Human IgG1(D239E,L241M)

Human Frizzled-5, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.