APC-Labeled Human HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Tetramer Protein, Biotin
Artikelnummer:
ABS-HL4-HA2E3-200UG
Hersteller Artikelnummer:
HL4-HA2E3-200ug
Alternativnummer:
ABS-HL4-HA2E3-200UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Biotin
MHC Class I molecules are expressed on nearly all nucleated cells and present peptides to cytotoxic Tcells (CD8+) to survey for infected or cancerous cells. MAGEA4 is normally silent in adult tissues (except testes and placenta) but is aberrantly expressed in various tumors (e.g., melanoma, lung cancer), making it a prime target for cancer immunotherapy, including Tcell therapies and vaccines. - Proteine/Peptide