APC-Labeled Human HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Tetramer Protein, Biotin
Biozol Catalog Number:
ABS-HL4-HA2E3-200UG
Supplier Catalog Number:
HL4-HA2E3-200ug
Alternative Catalog Number:
ABS-HL4-HA2E3-200UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Biotin
MHC Class I molecules are expressed on nearly all nucleated cells and present peptides to cytotoxic Tcells (CD8+) to survey for infected or cancerous cells. MAGEA4 is normally silent in adult tissues (except testes and placenta) but is aberrantly expressed in various tumors (e.g., melanoma, lung cancer), making it a prime target for cancer immunotherapy, including Tcell therapies and vaccines. - Proteine/Peptide
