Biotinylated Human HLA-A*02:01&B2M&hTERT (ILAKFLHWL) Complex Protein (Monomer, MALS verified)

Produktübersicht

• Artikelname: Biotinylated Human HLA-A*02:01&B2M&hTERT (ILAKFLHWL) Complex Protein (Monomer, MALS verified)
• Artikelnummer: ABS-HLT-H82E5-200UG
• Hersteller Artikelnummer: HLT-H82E5-200ug
• Alternativnummer: ABS-HLT-H82E5-200UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Biotin

Produktbeschreibung

hTERT (human Telomerase Reverse Transcriptase), the catalytic subunit of telomerase, maintains telomere length to drive tumor cells unlimited proliferation. It is highly expressed in ~8590% of cancers but silenced in most normal somatic cells. The peptide ILAKFLHWL (from hTERT residues 540548) acts as a tumorspecific antigen. It binds to MHC class I molecule HLAA0201 to form a surface complex on tumors, activating cytotoxic T lymphocytes (CTLs). The Human HLAA*0201 hTERT (ILAKFLHWL) complex protein is a complex of HLAA*0201 of the MHC Class I, B2M, and ILAKFLHWL peptide of the hTERT. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 36.3 kDa and 11.7 kDa
• Tag: C-10*His & C-Avi
• NCBI: 59606
• Puffer: PBS, pH7.4
• Reinheit: 95%
• Formulierung: Powder
• Target-Kategorie: HLA-A*0201 & B2M & hTERT (ILAKFLHWL)

Bilder

Immobilized Biotinylated Human HLA-A*02:01&B2M&hTERT (ILAKFLHWL) Complex Protein (Cat. No. HLT-H82E5) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Anti-HLA class I Antibody, Human IgG1 (W6/32) with a linear range of 0.1-2 ng/mL (QC tested).

Immobilized Biotinylated Human HLA-A*02:01&B2M&hTERT (ILAKFLHWL) Complex Protein (Cat. No. HLT-H82E5) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Anti-B2M Antibody, Human IgG1 with a linear range of 0.1-2 ng/mL (Routinely tested).

Biotinylated Human HLA-A*02:01&B2M&hTERT (ILAKFLHWL) Complex Protein on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.